The WUSM Structural Biology Core is a state of the art Macromolecular Crystallography Facility formed by the following WUSM Faculty Members:

To learn more about the Research Programs of these SBC Members please
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Dr. Gaya Amarasinghe
Assoc. Prof. of Pathology and Immunology
Laboratory & Genomic Medicine Dept.

Dr. Thomas Brett
Director Structural Biology Core
Asst. Prof. of Internal Medicine
Asst. Prof. of Cell Biology and Physiology
Asst. Prof. of Biochemistry and Molecular Biophysics
Internal Medicine – Pulmonary Dept.

Dr. Daved Fremont
Director Structural Biology Core
Prof. of Pathology & Immunology
Prof. of Biochemistry & Molecular Biophysics
Prof. of Molecular Microbiology & Microbial Pathogenesis
Pathology & Immunobiology Dept.

Dr. Dennis Hallahan
Elizabeth and James McDonnell Distinguished Professor and Head of the Department of Radiation Oncology
National Cancer Institute (NCI) Parent Committee Member
Leadership Committee of Siteman Cancer Center which oversees all research conducted in the Department of Radiation Oncology

Dr. Scott Hultgren
Helen L. Stoever Prof. of Molecular Microbiology & Microbial Pathogenesis
Molecular Microbiology & Microbial Pathogenesis Dept.

Dr. Weikai Li
Asst. Prof. of Biochemistry & Molecular Biophysics
Biochemistry & Molecular Biophysics Dept.

Dr. David Sibley
Prof. of Molecular Microbiology
Molecular Microbiology & Microbial Pathogenesis Program
Molecular Genetics and Genomics Program
Immunology Program

Dr. Chen Shen
Asst. Prof. of Medicine
Department of Molecular Microbiology

Resources open to member labs include a Rigaku X-ray generator, with two MAR345 image plate detectors supported with near liquid nitrogen cold heads, two TTP LabTech Mosquito robots, and a Rigaku HT Minstrel and CrystalMation Gallery. SBC non-members are encouraged to partner with SBC Members to learn structural techniques and then become SBC Members.

The Structural Biology Core also supports access to SBGRID (270+ structural biology applications running on Linux and OS X computers) Crystallographic Software, and access to a dedicated synchrotron beamline through membership in the MBC consortium at the Advanced Light Source in Berkeley CA (Beamline 4.2.2).